Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil.
نویسندگان
چکیده
INTRODUCTION In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil. METHODS Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed. RESULTS RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes. CONCLUSIONS Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.
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عنوان ژورنال:
- Revista da Sociedade Brasileira de Medicina Tropical
دوره 48 5 شماره
صفحات -
تاریخ انتشار 2015